Well the Windows WMF Exploit is in the wild and it looks like things will get worse until Microsoft releases a patch for this serious problem.
 
Here is a video of what this virus can do, http://www.websensesecuritylabs.com/images/alerts/wmf-movie.wmv

The MS Security Advisory: http://www.microsoft.com/technet/security/advisory/912840.mspx

The SANS Internet Storm Centre Article: http://isc.sans.org/diary.php?rss&storyid=996